Can Increased Melatonin lead to Diabetes
- Fatima Iqbal
- Feb 11, 2024
- 2 min read
A new study finds strong support for role of melatonin and one of its receptor MTNR1B in the development of Type 2 Diabetes. One of the variants of this receptor which is common in many individuals, was associated with increase in fasting glucose over time and predicted future chances of increased risk for Type 2 Diabetes, as a result of impairment of insulin secretion from pancreatic beta cell function. Notably, this effect was more pronounced with increasing age and increased demands imposed by increased age-related insulin resistance.
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